I tried guaifenesin (Mucinex)for several weeks because I always had a big clog of mucus low in my throat. It didn't do a thing. Turns out, the ENT suspects I have larygophageal reflux disease. He prescribed Aciphex to see if that will work. I am planning to try some of the remedies on this site first to see if I can deal with this naturally instead of pumping PPIs into my system.