I have been reading earth clinic for about a year now looking for relief of 15 plus years of debilitating migraines. About 8 months ago I started taking 400 mg. Of CoQ 10 everyday and for awhile I thought I had my migraines under control. It wasn't unusual for me to wake up every morning with one and some days they would last for 4 days with the nausea, vomiting, sensitivity to noise, smells and light. I notice they started letting up some and came less frequent and for shorter duration with the addition of the CoQ10 but I was still having them just less frequently. This is where I decided to add Nattokinase. I take one a day and it's 2000 FU. I have been on the Natto now for a little over 4 months and I have not had one single migraine. I felt I needed to shout to the world my experience. The migraines had ruled my life for so long. Kept me from living a normal life. I hope migraine sufferers will try this combo and see if it works for them. I know I have stumbled upon a miracle I have long prayed for. Hope this helps someone else.